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Pregled bibliografske jedinice broj: 423231

Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes

Briggs, Adrian W.; Good, Jeffrey M.; Green, Richard E.; Krause, Johannes; Maričić, Tomislav; Stenzel, Udo; Lalueza-Fox, Carles; Rudan, Pavao; Brajković, Dejana; Kućan, Željko et al.
Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes // Science, 325 (2009), 5938; 318-321 doi:10.1126/science.1174462 (međunarodna recenzija, članak, znanstveni)

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Naslov
Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes

Autori
Briggs, Adrian W. ; Good, Jeffrey M. ; Green, Richard E. ; Krause, Johannes ; Maričić, Tomislav ; Stenzel, Udo ; Lalueza-Fox, Carles ; Rudan, Pavao ; Brajković, Dejana ; Kućan, Željko ; Gušić, Ivan ; Schmitz, Ralf ; Doronichev, Vladimir B. ; Golovanova, Liubov V. ; de la Rasilla, Marco ; Fortea, Javier ; Rosas, Antonio ; Pääbo, Svante

Izvornik
Science (0036-8075) 325 (2009), 5938; 318-321

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neandertals ; mtDNA ; ancient DNA

Sažetak
Analysis of Neandertal DNA holds great potential for investigating the population history of this group of hominins, but progress has been limited due to the rarity of samples and damaged state of the DNA. We present a method of targeted ancient DNA sequence retrieval that greatly reduces sample destruction and sequencing demands and use this method to reconstruct the complete mitochondrial DNA (mtDNA) genomes of five Neandertals from across their geographic range. We find that mtDNA genetic diversity in Neandertals that lived 38, 000 to 70, 000 years ago was approximately one-third of that in contemporary modern humans. Together with analyses of mtDNA protein evolution, these data suggest that the long- term effective population size of Neandertals was smaller than that of modern humans and extant great apes.

Izvorni jezik
Engleski

Znanstvena područja
Geologija, Biologija, Etnologija i antropologija



POVEZANOST RADA

Projekti:
MZOS-101-2690680-2270 - Korelacija paleolitika mezolitika i neolitika kontinentalne i primorske Hrvatske (Brajković, Dejana, MZOS ) ( CroRIS)
MZOS-196-1962766-2751 - Populacijska struktura Hrvatske - antropogenetički pristup (Rudan, Pavao, MZOS ) ( CroRIS)

Ustanove:
Hrvatska akademija znanosti i umjetnosti,
Institut za antropologiju

Profili:

Avatar Url Dejana Brajković (autor)

Avatar Url Ivan Gušić (autor)

Avatar Url Željko Kućan (autor)

Avatar Url Pavao Rudan (autor)

Poveznice na cjeloviti tekst rada:

doi www.science.org

Citiraj ovu publikaciju:

Briggs, Adrian W.; Good, Jeffrey M.; Green, Richard E.; Krause, Johannes; Maričić, Tomislav; Stenzel, Udo; Lalueza-Fox, Carles; Rudan, Pavao; Brajković, Dejana; Kućan, Željko et al.
Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes // Science, 325 (2009), 5938; 318-321 doi:10.1126/science.1174462 (međunarodna recenzija, članak, znanstveni)
Briggs, A., Good, J., Green, R., Krause, J., Maričić, T., Stenzel, U., Lalueza-Fox, C., Rudan, P., Brajković, D. & Kućan, Ž. (2009) Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes. Science, 325 (5938), 318-321 doi:10.1126/science.1174462.
@article{article, author = {Briggs, Adrian W. and Good, Jeffrey M. and Green, Richard E. and Krause, Johannes and Mari\v{c}i\'{c}, Tomislav and Stenzel, Udo and Lalueza-Fox, Carles and Rudan, Pavao and Brajkovi\'{c}, Dejana and Ku\'{c}an, \v{Z}eljko and Gu\v{s}i\'{c}, Ivan and Schmitz, Ralf and Doronichev, Vladimir B. and Golovanova, Liubov V. and de la Rasilla, Marco and Fortea, Javier and Rosas, Antonio and P\"{a}\"{a}bo, Svante}, year = {2009}, pages = {318-321}, DOI = {10.1126/science.1174462}, keywords = {neandertals, mtDNA, ancient DNA}, journal = {Science}, doi = {10.1126/science.1174462}, volume = {325}, number = {5938}, issn = {0036-8075}, title = {Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes}, keyword = {neandertals, mtDNA, ancient DNA} }
@article{article, author = {Briggs, Adrian W. and Good, Jeffrey M. and Green, Richard E. and Krause, Johannes and Mari\v{c}i\'{c}, Tomislav and Stenzel, Udo and Lalueza-Fox, Carles and Rudan, Pavao and Brajkovi\'{c}, Dejana and Ku\'{c}an, \v{Z}eljko and Gu\v{s}i\'{c}, Ivan and Schmitz, Ralf and Doronichev, Vladimir B. and Golovanova, Liubov V. and de la Rasilla, Marco and Fortea, Javier and Rosas, Antonio and P\"{a}\"{a}bo, Svante}, year = {2009}, pages = {318-321}, DOI = {10.1126/science.1174462}, keywords = {neandertals, mtDNA, ancient DNA}, journal = {Science}, doi = {10.1126/science.1174462}, volume = {325}, number = {5938}, issn = {0036-8075}, title = {Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes}, keyword = {neandertals, mtDNA, ancient DNA} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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