Naslov
Antifungal and antimycotoxigenic properties of newly synthesized derivatives of coumarine

Autori
Duraković, S. ; Delaš, F. ; Govori, S. ; Kaljaj, V. ; Rapić, V. ; Kaljaj, L. ; Halt, M. ; Duraković, L.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Proceedings of 2nd International Congress Food Sciences & Food Biotechnology in Developing Countries / Rocha-Guzman, N. - Saltillo, 2006, 46-46

Skup
2nd International Congress Food Sciences & Food Biotechnology in Developing Countries

Mjesto i datum
Saltillo, Meksiko, 16.10.2006. - 18.10.2006

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Molds; mycotoxins; antifungal agents; coumarines

Sažetak
The effect of newly synthesized derivative of 11-hydroxy-7-imino-7H-7a, 12-diazbenzo/alfa/anthracen-6-one, on growth and aflatoxin B1 and G1 (AFB1 and AFG1) accumulation by toxigenic mold Aspergillus parasiticus NRRL 2999 was studied in yeast extract sucrose (YES) medium to determine the possible use of this compound as a mean of controlling aflatoxin accumulation. Experiments were carried out in a stationary culture at temperature of 28o C during 21 days. Mycelial dry weight were determined gravimetrically, and concentrations of AFB1 and AFG1 were measured by HPLC method using Hewlett-Packard instrument with fluorescence detector. Concentrations of investigated compound of 0.05 mmol x L-1 and 0.1 mmol x L-1, respectively, stimulated mold growth and AFB1 accumulation, but concentrations higher than 0.2 mmol x L-1 produced an inhibitory effect. In the presence of 0.3 mmol x L-1 of investigated coumarine, mold growth was decreased by 55% and toxin concentration by 85% or completely.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA