Naslov
Epilepsy and partial agenesis of corpus callosum (case report)

Autori
Šepić Grahovac, Dubravka ; Ružić Baršić, Antonija ; Grahovac, Tanja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Acta Neuropsychiatrica. Proceedings. 49th International Neuropsychiatric Pula Congress (INPC) 2009: 21 (Supplement 2): 73-94 / Vida Demarin, Vanja Bašić Kes, Zlatko Trkanjec. (ur.) - : Wiley-Blackwell, 2009, 78-78

Skup
The 49th International Neuropsychiatric Pula Congress (INPC)

Mjesto i datum
Pula, Hrvatska, 17.06.2009. - 20.06.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
epilepsy ; corpus callosum ; partial agenesis

Sažetak
Introduction/Objectives: Epilepsy may be caused by number of different ethyologies. Seizures of partial origin with or without secondary generalization mostly have an underlying structural lesion and it is very important to notice present focal neurological deficit. Congenital malformations of the brain linked to epileptic seizures are well described and manifested in variable clinical spectrum. The association between partial agenesis of corpus callosum (ACC) and epilepsy has not been described often. The impaired psychological functions and the diminished level of some cognitive functions in patients with epilepsy and ACC, especially memory are related. Participants, Materials/Methods: We present 35 year old, left-handed male with late onset of epilepsy presenting with secondary generalized seizures. In past history is information of neonatal central apnea. Neuroradiological features (MRI) were performed to exclude etiological factor for first seizure in his 31 years. Resulst: Brain MRI revealed the partial agenesis of corpus callosum. General physical evaluation and neurological examination showed excavated feet with shortened triceps tendon and mild bilateral pyramidal lesions. Our patient has lower cognitive status than average population and neuropsychological tests demonstrated mental retardation as result of organic cerebral dysfunction. Epilepsy becomes easily controlled after treatment with lamotrigine 200 mg twice daily. Conclusions: Late-onset epilepsy needs multidiscplinary approach because underlying precipitating factors are different and sometimes unexpected, as it has been shown in our patient.

Izvorni jezik
Engleski

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