Naslov
IMPETIGINIZATION OF BULLOUS PEMPHIGOID IN A FEMALE PATIENT WITH CHRONIC VENOUS ULCER

Autori
Marinović-Kulišić, Sanra ; Radoš, Jaka ; Lipozenčić, Jasna ; Milavec – Puretić, Višnja ; Tunuković, Suzana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstract Book 19th Conference of the European Wound Management Association: Healing, Educating, Learning and Preventing in Wound Care / - Helsinki, 2009

Skup
19th Conference of the European Wound Management Association: Healing, Educating, Learning and Preventing in Wound Care

Mjesto i datum
Helsinki, Finska, 20.05.2009. - 22.05.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
impetiginization; bullous pemphigoid; chronic venous ulcer; therapy

Sažetak
The aim of this case report is to point to the fact that chronic infected venous ulcer can be the cause of wound non-healing and a potential source of superinfection in patients with erosive dermatoses.A female patient aged 69 was admitted with deep chronic venous ulcer with discharge on the right leg, persisting for 20 years, extensive vesicobullous and erosive lesions of the oral cavity, trunk, gluteal and inguinal region, and bullae with turbid to purulent content on the hands. Soon upon admission, the patient turned febrile with elevated inflammatory parameters. The histopathologic and immunopathologic examinations indicated the diagnosis of bullous pemphigoid, while Tzanck test detected acantholytic dyskeratotic cells in the turbid to purulent content obtained from bullae. On bacteriologic culture, Staphylococcus aureus and group A beta-hemolytic streptococcus were isolated from the content of the bullae. Staphylococcus aureus was isolated in ulcer biopsy specimen. The patient was administered systemic corticosteroids in a dose of 0.5 mg/kg body weight, systemic antibiotics according to antibiotic sensitivity report, cloxacillin and azithromycin, and topical application of combined antibiotic-corticosteroid agents ; antiseptic dressings over venous ulcer ; enzymatic debridement ; and bio-occlusive dressings (silver hydrofiber). Two weeks of therapy introduction, the vesicobullous eruption subsided and erosions underwent partial epithelialization, whereas ulcer defect was filled with granulation tissue, with reduction in the size, swelling and redness of the surrounding skin, as well as in the level of pain, discharge and fetor. The use of antiseptic measures, ulcer covering with bio-occlusive dressings, and introduction of systemic antibiotics resulted in chronic venous ulcer healing and stopped impetiginization of bullous pemphigoid erosions. We presented the management of chronic venous ulcer with systemic antibiotics due to the clinical signs of critical ulcer colonization in bullous pemphigoid patient.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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