Pregled bibliografske jedinice broj: 417885
Radionuclide Captopril test in early detection of renovascular hypertension
Radionuclide Captopril test in early detection of renovascular hypertension // 4th Annual Meeting of the Croatian Society of Nuclear Medicine Technologists with International Participation "Nephrology in Nuclear Medicine"
Kraljevica, Hrvatska, 2009. (poster, međunarodna recenzija, sažetak, stručni)
CROSBI ID: 417885 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Radionuclide Captopril test in early detection of renovascular hypertension
Autori
Strnad, Dario ; Sabol, Ivica ; Gardašanić, Jasna ; Mihaljević, Ivan
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Skup
4th Annual Meeting of the Croatian Society of Nuclear Medicine Technologists with International Participation "Nephrology in Nuclear Medicine"
Mjesto i datum
Kraljevica, Hrvatska, 22.05.2009. - 24.05.2009
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
renovascular hypertension; captopril test procedures; radiofarmaceuticals
Sažetak
Renovascular hypertension (RVH) is one of the most prevalent causes of secondary hypertension, affecting up to 5% of the unselected hypertensive population. Causally, in RVH, functionally significant renal artery stenosis creates renal hypoperfusion which triggers the release of renin and secondary activation of the renin-ngiotensin-aldosterone axis. Consequently, RVH can be eliminated or substantially ameliorated following reversal of the stenosis by surgical or endovascular interventions. Historically, differential diagnosis of the RVH has been founded on selective renal arteriography and catheteric renal vein renin measurements. Patophysiologically, in the settings of ischaemic kidney, the vasopressor effect of angiotension II (All) on efferent arteriolar tone acts to maintain renal perfusion pressure, and by so, glomerular filtration (GF) rate. Conversely, the administration of captopril, an angiotensin convertase inhibitor that pre¬ vents production of All, decreases postglomerular vascular resistance, and thereby, reduces filtration pressure and GF rate. Simultaneously, effective renal plasma flow (ERPF) of the affected kidney is increased or remains unchanged. Here, captopril test procedures, radiofarmaceuticals and specific diagnostic findings are briefly reviewed. Criteria associ¬ ated with RVH and renal artery stenosis include worsening of the renogram curve, reduc¬ tion in relative uptake, a fall in GF rate, and prolongation of the renal parenchymal transit time in the settings of relatively preserved ERPF.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
