Naslov
Experimental evolution reveals natural selection on standing genetic variation

Autori
Teotonio, Henrique ; Chelo, Ivo M. ; Bradić, Martina ; Long, Anthony D.

Izvornik
Nature genetics (1061-4036) 41 (2009), 2; 251-257

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
effective population-size; drosophila-melanogaster; reverse evolution; adaptation; polymorphisms; fixation; locus

Sažetak
Evolution depends on genetic variation generated by mutation or recombination from standing genetic variation. In sexual organisms, little is known about the molecular population genetics of adaptation and reverse evolution(1-11). We carry out 50 generations of experimental reverse evolution in populations of Drosophila melanogaster, previously differentiated by forward evolution, and follow changes in the frequency of SNPs in both arms of the third chromosome. We characterize the effects of sampling finite population sizes and natural selection at the genotype level. We demonstrate that selection has occurred at several loci and further that there is no general loss or gain of allele diversity. We also observe that despite the complete convergence to ancestral levels of adaptation, allele frequencies only show partial return.

Izvorni jezik
Engleski

Znanstvena područja
Poljoprivreda (agronomija)

POVEZANOST RADA