Pregled bibliografske jedinice broj: 410347
Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations
Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations // PLOS genetics, 3 (2007), 6; 1108-1119 doi:10.1371/journal.pgen.0030103 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 410347 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations
(Phenotype frequencies of autosomal minor
histocompatibility antigens display significant
differences among populations)
Autori
Spierings, Eric ; Hendriks, Matthijs ; Absi, Lena ; Canossi, Angelica ; Chhaya, Sonal ; Crowley, John ; Dolstra, Harry ; Eliaou, Jean-Francois ; Ellis, Tom ; Enczmann, Jurgen ; Fasano, Maria E. ; Gervais, Thibaut ; Gorodezky, Clara ; Kircher, Brigitte ; Laurin, David ; Leffell, Mary S. ; Loiseau, Pascale ; Malkki, Mari ; Markiewicz, Miroslaw ; Martinetti, Miryam ; Maruya, Etsuko ; Mehra, Narinder ; Oguz, Fatma ; Oudshoorn, Machteld ; Pereira, Noemi ; Rani, Rajni ; Sergeant, Ruhena ; Thomson, Jackie ; Tran, Thuong Hien ; Turpeinen, Hannu ; Yang, Kuo-Liang ; Žunec, Renata ; Carrington, Mary ; de Knijff, Peter ; Els Goulm
Izvornik
PLOS genetics (1553-7390) 3
(2007), 6;
1108-1119
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
HA-1 ; HA-2 ; PCR-SSP ; population study
Sažetak
Minor histocompatibility (H) antigens are allogeneic target molecules having significant roles in alloimmune responses after human leukocyte antigen– matched solid organ and stem cell transplantation (SCT). Minor H antigens are instrumental in the processes of transplant rejection, graft-versus-host disease, and in the curative graft-versus-tumor effect of SCT. The latter characteristic enabled the current application of selected minor H antigens in clinical immunotherapeutic SCT protocols. No information exists on the global phenotypic distribution of the currently identified minor H antigens. Therefore, an estimation of their overall impact in human leukocyte antigen– matched solid organ and SCT in the major ethnic populations is still lacking. For the first time, a worldwide phenotype frequency analysis of ten autosomal minor H antigens was executed by 31 laboratories and comprised 2, 685 randomly selected individuals from six major ethnic populations. Significant differences in minor H antigen frequencies were observed between the ethnic populations, some of which appeared to be geographically correlated.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
MZOS-214-0000000-3573 - Uloga gena non-HLA u transplantaciji tkiva i organa (Žunec, Renata, MZOS ) ( CroRIS)
Ustanove:
Klinički bolnički centar Zagreb
Profili:
Renata Žunec
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE