Naslov
Signalling by neuronal tyrosine kinase receptors : Relevance for development and regeneration

Autori
Hausott, Barbara ; Kurnaz, Isil ; Gajović, Srećko ; Klimaschewski, Lars

Izvornik
Anatomical record-advances in integrative anatomy and evolutionary biology (1932-8486) 292 (2009), 12; 1976-1985

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
tyrosine kinase; receptors; neurons
(tyrosine kinase; receptors; neruons)

Sažetak
Receptor tyrosine kinase activation in response to binding of neurotrophic factors determines neuronal morphology and identity, migration of neurons to appropriate destinations and integration into functional neural circuits as well as synapse formation with appropriate targets at the right time and at the right place. This review summarizes the most important aspects of the intraneuronal signalling mechanisms and induced gene expression changes that underlie the morphological and neurochemical consequences of receptor tyrosine kinase activation in central and peripheral neurons.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA