Pregled bibliografske jedinice broj: 407961
Comparison of propolis of different geographic origin
Comparison of propolis of different geographic origin // Young Pharmaceutical Scientists Meet in Nice Nice, Pre-Satellite Meeting of the PharmSciFair / J. Siepmann i sur. (ur.).
Nica: APGI – International Society of Drug Delivery Sciences and Technology, 2009. str. 63p (64w)-64 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 407961 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Comparison of propolis of different geographic origin
Autori
Bojić, Mirza ; Simon Haas, Vicente ; Medić-Šarić, Marica
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Young Pharmaceutical Scientists Meet in Nice Nice, Pre-Satellite Meeting of the PharmSciFair
/ J. Siepmann i sur. - Nica : APGI – International Society of Drug Delivery Sciences and Technology, 2009, 63p (64w)-64
Skup
Young pharmaceutical scientists meet in Nice, Pre-Satellite Meeting of the PharmSciFair
Mjesto i datum
Nica, Francuska, 07.06.2009. - 08.06.2009
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
prirodni produkti; kvaliteta; ragulativa
(natural products; quality; regulatory affairs)
Sažetak
Purpose: Standardization of natural products is one of the key objectives for assuring quality and necessity for registration as medicinal products. During the last two years we have developed procedures for standardization of propolis tinctures from Croatia. Before setting the limits to be used in certificate of analysis we wanted to check weather propolis of other than Croatian origin will pass the quality control tests for content of polyphenolics as these are major pharmacologically active substances. Methods: For the identification and quantification of individual polyphenolic TLC densitometry in situ was used. Total content of flavonoids was determined using Christ-Müller’ s method and phenolic acids were determined according to European Pharmacopoeia. Results: Chrysin, caffeic and p-coumaric acid were identified and determined in Croatian propolis. None of the 14 polyphenolics analysed was identified in Brazilian sample. Total content of flavonoids was cca. 40 times grater while the content of phenolic acids was cca. 6 times lower in Croatian compared to Brazilian propolis. Conclusion: Simple application of standardized procedures for Croatian propolis is not possible for propolis samples of different origin. The results indicate that qualitative and quantitative content of active substances is significantly different between Croatian and Brazilian propolis.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Projekti:
006-0061117-1237 - Biološki aktivni spojevi, metaboliti i QSAR (Medić-Šarić, Marica, MZOS ) ( CroRIS)
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
