Pregled bibliografske jedinice broj: 405416
Adjuvant endocrine therapy for perimenopausal women with early breast cancer
Adjuvant endocrine therapy for perimenopausal women with early breast cancer // Breast, 18 (2009), 1; 2-7 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 405416 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Adjuvant endocrine therapy for perimenopausal women with early breast cancer
Autori
Ortmann, O. ; Čufer, Tanja ; Dixon, J.M. ; Maas, N. ; Marchetti, P. ; Pagani, O. ; Pronzato, P. ; Semiglazov, V. ; Spano, J.P. ; Vrdoljak, Eduard ; Wildiers, H.
Izvornik
Breast (0167-6806) 18
(2009), 1;
2-7
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
breast cancer; perimenopausal; endocrine therapy
Sažetak
Adjuvant treatment with aromatase inhibitors (AIs) improves outcomes in postmenopausal women with hormone-sensitive early breast cancer compared with tamoxifen. However, AIs should not be used in premenopausal women because they can paradoxically increase estrogen secretion and may therefore stimulate tumor progression. In perimenopausal women undergoing treatment for breast cancer, it can be difficult to determine true menopausal status because adjuvant chemotherapy, tamoxifen, and gonadotropin-releasing hormone analogues can induce transient (or permanent) ovarian suppression. How can one determine whether these women are truly postmenopausal and therefore candidates for AI therapy? A panel of experts in the field of endocrine therapy in breast cancer met in Dubrovnik, Croatia, on October 23, 2006, to discuss this clinical dilemma. This report summarizes the conclusions and recommendations that arose from this discussion.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
216-0000000-0484 - Dvostruki model ovarijalne kancerogeneze - molekularna i morfološka studija (Tomić, Snježana, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Split
Profili:
Eduard Vrdoljak
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE