Pregled bibliografske jedinice broj: 404805
A critical size for palindrome induced intrachromosomal recombination in yeast
A critical size for palindrome induced intrachromosomal recombination in yeast // Environmental mutagens and human health
Zagreb, 2008. str. 189-189 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 404805 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
A critical size for palindrome induced intrachromosomal recombination in yeast
Autori
Lisnić, Berislav ; Svetec, Ivan-Krešimir ; Štafa Anamarija ; Zgaga, Zoran.
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Environmental mutagens and human health
/ - Zagreb, 2008, 189-189
Skup
38th Annual Meeting of European Environmental Mutagen Society
Mjesto i datum
Cavtat, Hrvatska, 21.09.2008. - 25.09.2008
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Palindromic sequences; Genetic stability; Yeast; Saccharomyces cerevisiae; COM1/SAE2; Recombination
Sažetak
While short palindromes are important DNA motifs frequently found in different cis-acting genetic elements longer palindromic sequences are highly unstable in various organisms. SInce recombinogenicity of a palindrome is clearly size-related we decided to investigate how thw step-by-step increase in the size of a palindrome introduced in the yeast genome will affect its genetic stability. We studied the influence of palindrome size on recombination between two directly repeated copies of the yeast CYC1 gene leading to the loss of the intervening sequence ("pop-out" recombination).
Izvorni jezik
Engleski
Znanstvena područja
Biotehnologija
POVEZANOST RADA
Projekti:
058-0580477-2258 - Palindromi u genomima i mehanizmi zamjene gena u kvasca (Krešimir Svetec, Ivan, MZOS ) ( CroRIS)
Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb