Pregled bibliografske jedinice broj: 399131
New insights into maternal-fetal interactions at implantation
New insights into maternal-fetal interactions at implantation // Reproductive biomedicine online, 2 (2001), 3; 198-203 (podatak o recenziji nije dostupan, članak, znanstveni)
CROSBI ID: 399131 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
New insights into maternal-fetal interactions at implantation
Autori
Chaouat, Gerard ; Zourbas, Sandrine ; Ostojić, Saša ; Lapprée Delage, Genevieve ; Dubanchet, Sylvie ; Ledee-bataille, Natalie ; Martal, Jacques
Izvornik
Reproductive biomedicine online (1472-6491) 2
(2001), 3;
198-203
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Cytokines; Immunology; Implantation; Materno– fetal interactions; Pregnancy
(cytokines; immunology; implantation; materno– fetal interactions; pregnancy)
Sažetak
The immunotrophic theory was enunciated by Tom Wegmann. Since then, the involvement of cytokines in implantation and materno-fetal tolerance has emerged as a central topic in reproductive immunology. This brief survey covers the historical background leading to the specification of the crucial role of cytokines at the feto-maternal interface, and the present known patterns of their function. Focus is addressed to the most recent concept, e.g. pregnancy as a Th2 phenomenon (the immune response of the mother is biased towards the production of anti inflammatory cytokines, amongst them IL-10 which suppress inflammatory responses). A brief description of the role of inflammatory cytokines in implantation is presented to explain why it does not fit into such a scheme, and other recent data, for example on gamma interferon, also fails to accord with the Th2 phenomenon.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
