Naslov
Changes in corpus callosum area in children with perinatal brain injury in relation to echogenicity of periventricular crossroads

Autori
Benjak, Vesna ; Čuljat, Marko ; Pavlović, Maja ; Kostović-Srzentić Mirna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Neurologia Croatica / - , 2007

Skup
Drugi hrvatski kongres neuroznanosti

Mjesto i datum
Zagreb, Hrvatska, 18.05.2007. - 19.05.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
corpus callosum; crossroad of pathways; magnetic resonance; ultrasound

Sažetak
There is a high incidence of periventricular leukomalatia caused by hypoxia-ischemia in preterm infants. These lesions damage the periventricular crossroads of commissural, projection and associative pathways, which are in close anatomical relationship with lateral ventricles. We explored to what extent the abnormalities of echogenicity of the periventricular crossroads of pathways correlate with changes of commissural pathways of the corpus callosum. Our study included nine infants (26-41 weeks of gestation) with prospective perinatal brain injury. The areas of frontal, main and occipital crossroads were readily visualized by cranial ultrasound scans, performed during the first two weeks after birth. The corpus callosum area measurements were performed using magnetic resonance images, acquired between the first and sixth postnatal month (postmenstrual age 40-49 weeks). We found a trend of correlation between the increased echogenicity in the crossroad areas and the decrease of the corpus callosum midasgittal area, with a statistical significance p<0.05. This supports the hypothesis that callosal fibers may be damaged, while growing through the periventricular crossroads of pathways.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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