Pregled bibliografske jedinice broj: 398575
Implantation : can immunological parameters of implantation failure be of interest for pre-eclampsia?
Implantation : can immunological parameters of implantation failure be of interest for pre-eclampsia? // Journal of reproductive immunology, 59 (2003), 2; 205-217 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 398575 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Implantation : can immunological parameters of implantation failure be of interest for pre-eclampsia?
Autori
Chaouat, Gerard ; Ledee-bataille, Natalie ; Zourbas, Sandrine ; Dubanchet, Sylvie ; Sandra, Olivier ; Martal, Jacques ; Ostojić, Saša ; Frydman, René
Izvornik
Journal of reproductive immunology (0165-0378) 59
(2003), 2;
205-217
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
cytokines; networks; implantation; paradigm; human
Sažetak
We restate briefly why we consider that the Th1/Th2 paradigm, as useful as it has been, is now no longer adequate and is obsolete. We take as an example the role of IL-18, abortifacient at high doses but cardinal for the control of natural killer (NK) cell effects on spiral artery remodelling in mice, and likely also in humans. We then describe briefly our recent studies on cytokine defects and implantation failure in humans, a key feature being the link between uterine cytokine dysregulation and abnormal uterine vascular scores. We draw lessons for preeclampsia, and describe features of a model for its immune aetiology.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
