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Pregled bibliografske jedinice broj: 395529

Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA

Rusak, Gordana; Piantanida, Ivo; Bretschneider, Sabine, Ludwig-Müller, Jutta
Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA // Journal of Inorganic Biochemistry, 103 (2009), 12; 1597-1601 doi:10.1016/j.jinorgbio.2009.08.008 (međunarodna recenzija, članak, znanstveni)

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Naslov
Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA

Autori
Rusak, Gordana ; Piantanida, Ivo ; Bretschneider, Sabine, Ludwig-Müller, Jutta

Izvornik
Journal of Inorganic Biochemistry (0162-0134) 103 (2009), 12; 1597-1601

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Flavonoids ; Rare Earth Metals ; Cucumber Mosaic Virus ; Nucleic Acids

Sažetak
Due to broad spectrum of biological activities of flavonoids, their target molecules in the cell are intensively studied. We examined the interactions of flavonoid quercetin (Q) and its lanthanum complex (QLa3+) with plant viral satellite (sat) dsRNA. Comparison of the cumulative binding and the estimated intercalative binding constant pointed towards an additional binding mode of quercetin to exclusively viral dsRNA, which is not recorded for synthetic dsRNAs. The QLa3+ showed significantly higher affinity toward viral dsRNA than Q and La3+ alone, most likely as the consequence of quercetin intercalation accompanied by additional electrostatic interaction of La3+ with the negatively charged viral RNA backbone.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija



POVEZANOST RADA

Projekti:
098-0982914-2918 - Dizajn, sinteza i ispitivanje interakcija malih molekula s DNA, RNA i proteinima (Piantanida, Ivo, MZOS ) ( CroRIS)
119-1191192-1213 - Flavonoidi i molekularni mehanizmi njihovih bioloških učinaka (Rusak, Gordana, MZOS ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Ivo Piantanida (autor)

Avatar Url Gordana Rusak (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com doi.org

Citiraj ovu publikaciju:

Rusak, Gordana; Piantanida, Ivo; Bretschneider, Sabine, Ludwig-Müller, Jutta
Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA // Journal of Inorganic Biochemistry, 103 (2009), 12; 1597-1601 doi:10.1016/j.jinorgbio.2009.08.008 (međunarodna recenzija, članak, znanstveni)
Rusak, G., Piantanida, I. & Bretschneider, Sabine, Ludwig-Müller, Jutta (2009) Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA. Journal of Inorganic Biochemistry, 103 (12), 1597-1601 doi:10.1016/j.jinorgbio.2009.08.008.
@article{article, author = {Rusak, Gordana and Piantanida, Ivo}, year = {2009}, pages = {1597-1601}, DOI = {10.1016/j.jinorgbio.2009.08.008}, keywords = {Flavonoids, Rare Earth Metals, Cucumber Mosaic Virus, Nucleic Acids}, journal = {Journal of Inorganic Biochemistry}, doi = {10.1016/j.jinorgbio.2009.08.008}, volume = {103}, number = {12}, issn = {0162-0134}, title = {Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA}, keyword = {Flavonoids, Rare Earth Metals, Cucumber Mosaic Virus, Nucleic Acids} }
@article{article, author = {Rusak, Gordana and Piantanida, Ivo}, year = {2009}, pages = {1597-1601}, DOI = {10.1016/j.jinorgbio.2009.08.008}, keywords = {Flavonoids, Rare Earth Metals, Cucumber Mosaic Virus, Nucleic Acids}, journal = {Journal of Inorganic Biochemistry}, doi = {10.1016/j.jinorgbio.2009.08.008}, volume = {103}, number = {12}, issn = {0162-0134}, title = {Complex formation of quercetin with lanthanum enhances binding to plant viral satellite double stranded RNA}, keyword = {Flavonoids, Rare Earth Metals, Cucumber Mosaic Virus, Nucleic Acids} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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