Pregled bibliografske jedinice broj: 39405
Regioselective epimerisation of cis-3-Amino-4-oxo-azetidine-2-sulphonic acid and synthesis of monocyclic β-lactams
Regioselective epimerisation of cis-3-Amino-4-oxo-azetidine-2-sulphonic acid and synthesis of monocyclic β-lactams // Tetrahedron, 56 (2000), 24; 3985-3993 doi:10.1016/s0040-4020(00)00298-2 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 39405 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Regioselective epimerisation of cis-3-Amino-4-oxo-azetidine-2-sulphonic acid and synthesis of monocyclic β-lactams
Autori
Cerić, Helena ; Kovačević, Miće ; Šindler-Kulyk, Marija
Izvornik
Tetrahedron (0040-4020) 56
(2000), 24;
3985-3993
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
azetidinones ; epimerisation ; imines ; sydnones
Sažetak
A novel procedure for the regioselective epimerisation of cis-3-amino-4-oxo-azetidine-2-sulphonic acid (3-AAA)into the trans-isomer is described. It was found that a compolete inversion of C-3 configuration of the cis-3-AAA takes place during the formation of a Schiff base. The cleavage of the imine bond of the Schiff base in methanol resulted in the generation of trans-3-AAA in good yield. Here is also described a preparation of novel cis- and trans-monobactams with an amidosulphonic acid group on azetidinone nitrogen.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
125004
Ustanove:
Pliva-Istraživački institut,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
Uključenost u ostale bibliografske baze podataka::
- CA Search (Chemical Abstracts)
