Naslov
Modelling of a Multi-enzyme System

Autori
Tichy, S. ; Vasić-Rački, Đurđa ; Schutte, H. ; Talsky, G. ; Wandrey, Christian

Izvornik
Chemical and biochemical engineering quarterly (0352-9568) 1 (1987); 25-30

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
optimization; mathematical modeling; methionine production

Sažetak
Methionine production from racemic mixtures of alpha -hydroxy acids has been fully optimized by the modeling of the reaction and the enzyme membrane reactors. A detailed kinetic evaluation was carried out to determine the kinetic expression. To predict the performance of a continuously operated enzyme membrane reactor for the production of methionine, the mass balances of all reaction components were set up for a continuous stirred tank reactor. The reactor model was used to estimate the relationship between the steady state substrate conversion and the enzyme ratio, concentration of alpha -keto-acid and polyethyleneglycol bound coenzyme and residence time. The effect of conversion on the reactor productivity was also studied using the developed model.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA