Naslov
The mutagenic potential of AH+ and AH26 by salmonella/microsome assay

Autori
Jukić, Silvana ; Miletić, Ivana ; Anić, Ivica ; Britvić, Smiljana ; Osmak, Maja ; Sistig, Suzana

Izvornik
Journal of endodontics (0099-2399) 26 (2000), 6; 321-324

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
root-canal sealers ; sealing properties ; mcrosome assay ; formaldehyde

Sažetak
The aim of this study was to examine the mutagenic potential of canal sealers AH+ and AH26 by Salmonella/microsome assay. The materials were tested immediately after mixing, 1 hr and 1 month later, respectively. The dimethyl sulfoxide extracts of sealers in amounts of 3.0, 1.5, and 0.75 mu l/plate were used. The plated bacterial strains of Salmonella were TA 98 and TA 100. The results showed that AH+ is mutagenic toward strain TA 100 1 hr after mixing. One month after mixing, mutagenic activity was expressed only in TA 98. Paste A showed strong mutagenicity toward TA 100, AH26 was more mutagenic to the TA 100 immediately after mixing, 1 hr later, and 1 month after it was polymerized. Also it was mutagenic toward TA 98 in the polymerized condition. further examinations should be conducted to establish a definitive conclusion about mutagenic potential for these two endodontic materials. [References: 19]

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija

POVEZANOST RADA