Naslov
Cytogenetic changes in subjects occupationally exposed to benzene

Autori
Kašuba, Vilena ; Rozgaj, Ružica ; Šentija, Karmela

Izvornik
Chemosphere (0045-6535) 40 (2000), 3; 307-310

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
OCCUPATIONAL EXPOSURE; CHROMOSOMAL ABERRATIONS; SISTER CHROMATID EXCHANGE; BENZENE

Sažetak
Humans are exposed to benzene from various occupational and environmental sources. The genotoxic effects of benzene were assessed in peripheral blood lymphocytes of 36 workers employed in the shoe industry for a period extending from seven months to over 30 years. Chromosomal aberrations and sister chromatide exchanges were used as indicators of genotoxic effects. The incidence of dicentric chromosomes in the exposed group was significantly higher than in the control group (P<0.05). No significant increase was detected between the working period in the exposed group and chromosomal aberrations. Sister chromatid exchange (SCE) frequency was not significantly increased in the exposed group.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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