Pregled bibliografske jedinice broj: 388849
Changes in the quantity of cathepsin D in irradiated human cells following treatment with hyperthermia and interferon
Changes in the quantity of cathepsin D in irradiated human cells following treatment with hyperthermia and interferon // 1st Slovene Microbiological Congress with International participation
Bled, Slovenija, 1993. (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 388849 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Changes in the quantity of cathepsin D in irradiated human cells following treatment with hyperthermia and interferon
Autori
Ferle Vidović, Ana ; Kaštelan, Marija ; Petrović, Danilo ; Vrhovec, Ivan ; Škrk, Janez
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
1st Slovene Microbiological Congress with International participation
Mjesto i datum
Bled, Slovenija, 24.10.1993. - 27.10.1993
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Cathepsin D; Irradiated human cells; Treatment; Hyperthermia; Interferon
(cathepsin D; irradiated human cells; treatment; hyperthermia; interferon)
Sažetak
In the present work, the changes in quantity of cathepsin D, an aspartic proteinase, in proliferating human nonmalignant (HEF) and malignant (HEP2) cells after combined treatment by gamma irradiation, hyperthermia and by interferon α -2b (IFN α ) were analyzed. Correlation between the antiproliferative effects of these combined agents in the concentrations of this cathepsin D was expected. Evidently, the treatment of cells in culture by IFNα , combined with irradiation and elevated temperature, produces an increased quantity of cathepsin D. In nonmalignant HEF cells these effects are more expressed than in malignant Hep2 cells.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Klinički bolnički centar Rijeka
