Naslov
Left atrial spontaneous echo contrast in mitral stenosis with sinus rhythm

Autori
Matana, Ante ; Zaputović, Luka ; Mavrić, Žarko ; Žagar, Davorka ; Matana, Zrinka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Acta Clinica Croatica. Suplement 1 / - Zagreb, 2001, 123-123

Skup
9th Alpe Adria Cardiology Meeting

Mjesto i datum
Dubrovnik, Hrvatska; Cavtat, Hrvatska, 06.06.2001. - 09.06.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Left atrial spontaneous echo contrast; Mitral stenosis; Sinus rhythm

Sažetak
The risk of thromboembolism (TE) in patients with mitral stenosis (MS) and atrial fibrillation (AF) is eighteen times greater than in healthy persons. Anticoagulant therapy (ACT) is regularly administered in these patients. Although the risk of TE is about four times higher in patients with MS and preserved sinus rhythm (SR) than in healthy persons, there is no proof that in these patients ACT decreases this risk. In this study, a group of 15 patients with MS were analyzed. Eight patients had permanent AF, and seven had preserved SR. The patients with AF were older than those with SR (57 ; 9 vs. 45 ; 11 years, p=0.03), otherwise there were no significant differences between the patients with AF and those with SR. However the limiting factor was the small number of patients in both groups. Although not significant, in patients with SR the trend of a larger mitral valve area was found (1.04 ; 0.32 cm2 in patients with AF vs. 1.27 ; 0.31 cm2 in those with SR, p=0.13). During transesophageal echocardiography (TEE), left atrial spontaneous echo contrasts (LASEC) was found in all patients with AF and in 4 (57%) patients with SR (p=0.058). All patients had minor mitral regurgitation not over the level of 2+. Left atrial appendange thrombus was found only in 2 (25%) patients with AF (p=0.18). All patients with AF received ACT only one such patient having a history of TE before the introduction of ACT. The patients with SR, neither experienced any episode of TE nore received ACT. Earlier studies have not justified ACT in patients with MS and preserved SR. However in some of them LASEC was present. LASEC, left atrial thromby and TE are closely related phenomenon. Now its possible to identified the patients with MS in SR with an increased risk for TE, in whome the use of ACT would be reasonable. At this time, TEE may have a decisive role.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA