Naslov
Disaccharidases in jejunal mucosa of children

Autori
Lutkić, Aleksandar ; Šir, Stanko ; Varga, Lidija ; Primer, Snježana ; Turk, Ranka ; Shi, Lin-Yi ; Peršić, Mladen ; Votava, Ana

Izvornik
Acta pharmaceutica Iugoslavica (0001-6667) 35 (1985); 61-69

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Disaccharidases ; jejunal mucosa ; children

Sažetak
Peroral small-intestinal biopsy was carried out on 112 paediatric patients observed because of malapsorption syndrome. Disaccharidase activities of lactase, sucrase, maltase, isomaltase, palatinase, trehalase, and cellobiase were assayed by the procedure worked out in our laboratory. The results obtained show that 35 of patients exibit normal values of activities of disaccharidases, and that 37 of coelic sprue patients exibit generalised deficiency of all the disaccharidases. The activity ratios of some enzymes indicating the relative ability of mucosa to hydrolise alfa-glucosidic, beta-glucosidic, and beta-galactosidic bonds are discussed. The lactase/trehalase activity ratio may serve as an indicator of lactase deficiency.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA