Naslov
Glycobiology of Stress

Autori
Lauc, Gordan ; Flögel, Mirna

Izvornik
Encyclopedia of Stress ; Vol 2 ; Fink, George (Ed.) ; San Diego : Academic Press ; 276-282 ; ISBN 0-12-226735-4 (three volume set)

Vrsta, podvrsta
Ostale vrste radova, natuknica u enciklopediji, leksikonu, rječniku i sl.

Godina
2000

Ključne riječi
Phycholigical stress; diseases; cell response

Sažetak
Psychological stress is associated with numerous diseases, but molecular mechanisms linking stress to the development of ill symptoms are still mostly obscure. Stress alert is conveyed by hormonal signals throughout the body, yet a particular cell response to a hormonal signal is not determined by the signal itself, but by the molecular composition, energy content, and by the physiological role and current status of the target cell. Stress induced changes in glycoconjugate structures and expression of their receptors lectins appear to be the most obvious molecular consequences of stress experience. Though at the moment only little is known about the metabolic steps leading to these changes, there is evidence that activities of glycosyltransferases are also affected by stress. Since there is no doubt that many vital physiological processes and disorders strongly depend on glycoconjugate-receptor interactions, it seems only justified to assume that glycosylation changes contribute to the development of diseases that are associated with stress.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti

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