Naslov
Structural abnormalities of chromosome 1 in acute myeloid leukemia with lymph node involvment

Autori
Kušec, Rajko ; Lasan, R. ; Kardum-Skelin, Ika ; Ostojić, Slobodanka ; Vrhovac, Radovan ; Gašparov, Slavko ; Kardum, Mirjana Mariana ; Minigo, Hrvoje ; Jakšić, Branimir ; Hitrec, Vlasta

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Cytogenetics Conference, 2nd Conference : Abstracts, in Cytogenetic and Cell Genetics, Vol. 85, No. 1-2 / - Basel : Karger Publishers, 1999, 77-77

Skup
Second European Cytogenetics Conference

Mjesto i datum
Beč, Austrija, 03.07.1999. - 06.07.1999

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Chromosome 1 ; myeoloid leukemia ; lymphoid involvment

Sažetak
A younger male patient presented with acute leukemia of myeloid morphology (M2) with unusual clinical presentation of affection of lymphatic nodes, mediastinum and spleen. Immunophenotypicaly same antigen expression on blasts was found in BM, PB and biopsized lymph node. Cytogentics detected 46, xy, der (1) hsr(1 ; 1)(p11 ; ?)+6, del(6))p21=, -13, add(17p). Highly unusal and extensive involvment of chromosome 1 material in this complex karyotype suggest that some of the abberant genetic information related to Chromosome 1 in this patients might be responible for unusual hematological behaviour of the tumour

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA