Naslov
Comparison of frequency of apoptosis and DNA damage in X-irradiated human peripheral blood mononuclear cells from donors of various ages

Autori
Chauvin, Christian ; Heidenreich, Evelyn ; Elmendorf-Dreikorn, Kristina ; Slor, Hanoch ; Kutzner, Joachim ; Batel, Renato ; Schroder, Heinz, C.

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Development of Methods for Determination of Radiosensitivity / Schroder, Heinz, C. ; Muller, Werner, E.G. - Mainz : Akademie Gemeinnutziger Wissenschaften, Erfurt, 1998, 96-107

Skup
Development of Methods for Determination of Radiosensitivity

Mjesto i datum
Mainz, Njemačka, 06.06.1998

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
apoptosis;DNA damage;X-irradiation;human blood;ageing

Sažetak
In this study, the age-dependent changes of the basal levels and X-radiation-induced levels of apoptosis were determined in parallel with the age-dependent changes of the basal levels and X-radiation-induced levels of DNA single-strand breaks in human peripheral blood mononuclear cells (PBMC).DNA damage was analysed using Fast Micromethod and apoptosis was determined using Cell Death Detection ELISA. The results show that there is no correlation between the levels of irradiation-induced apoptosis and DNA single.strand breaks in individuals of different age.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

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