Naslov
Komparativna genomika pokazuje da najjednostavnije višestanične životinje - spužve (Porifera) imaju širok repertoar gena
(Comparative genomics reveals broad genetic repertoire of simplest metazoans – sponges (Porifera))

Autori
Harcet, Matija ; Ćetković, Helena ; Perina, Dragutin ; Müller, Werner ; Vlahoviček, Kristian

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Zbornik sažetaka znanstvenog simpozija 50 godina molekularne biologije u Hrvatskoj / Zahradka, K ; Plohl, M ; Ambriović-Ristov, A - Zagreb : Institut Ruđer Bošković, 2008

ISBN
978-953-6690-78-7

Skup
50 godina molekularne biologije u Hrvatskoj

Mjesto i datum
Zagreb, Hrvatska, 20.11.2008. - 21.11.2008

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
spužve; Porifera; genomi; Suberites domuncula
(sponges; Porifera; genome; Suberites domuncula)

Sažetak
Sponges (Porifera) are the simplest extant and probably the earliest branching metazoan phylum. In order to evaluate sponge genetic complexity and consequently the genetic complexity of the common ancestor of all Metazoa (Urmetazoa) and to further elucidate metazoan genome evolution, we employed random EST sequencing approach. Two demosponge species were used for the analyses – Suberites domuncula with 4646 and Lubomirskia baicalensis with 1335 unique transcript sequences. We identified and compared sponge protein homologues from six model organisms with complete genome sequences: Nematostella vectensis, Caenorhabditis elegans, Drosophila melanogaster, Strongylocentrotus purpuratus, Ciona intestinalis and Homo sapiens. Our results strongly indicate that, measured by gene content, sponges have complex genomes. This finding implies that the ancestor of all metazoans (Urmetazoa) also had a complex genome.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

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