Naslov
Transient hyperphosphatasemia in an infant with bronchiolitis and pneumonia

Autori
Dodig, Slavica ; Demirović, Jadranka ; Jelčić, Žaneta ; Richter, Darko ; Čepelak, Ivana ; Zrinski Topić, Renata ; Petrinivić, Rajka

Izvornik
European journal of medical research (0949-2321) 13 (2008), 11; 536-538

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
transient hyperphosphatasemia; bronchiolitis; pneumonia
(prolazna hiperfosfatazemija; bronhiolitis; pneumonija)

Sažetak
We present benign transient hyperphosphatasemia in a 4-month old infant with acute bronchiolitis and pneumonia. During hospitalization the infant had increased catalytic activity of the ALP: 2nd day-5074 U/L, 3rd day 5622-U/L, 8th day-3129 U/L. The X-ray, leukocytosis, and CRP pointed to bacterial etiology of the respiratory disorder. Electrophoretic separation revealed atypical isoenzyme profile: fast anodal, near-cathodal and bone fractions. ALP levels normalized within 54 days, and control electrophoresis revealed the appearance of normal liver, placental/placental-like, intestinal and bone isoenzymes. The appearance of an atypical fast anodal and near-cathodal fractions of ALP in this infant during an acute lower respiratory tract infection and rapid return within the reference intervals points to benign transient hyperphosphatasemia.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Farmacija

POVEZANOST RADA