Naslov
VASCULAR ORIGINS OF DEMENTIA

Autori
Budišić, Mislav ; , Jurasic, Miljenka-Jelena ; Martinic Popovic, Irena ; Morović, Sandra ; Šerić, Vesna ; Bene, Raphael ; Demarin, Vida

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Neurologia Croatica 57 (Suppl. 4) / Šimić, Goran ; Mimica, Ninoslav ; Petravić, Damir - Zagreb : Denona, 2008

Skup
4th Croatian Congress on Alzheimer's disease with international participation

Mjesto i datum
Rovinj, Hrvatska, 08.10.2008. - 11.10.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
vascular; hyperlipoproteinaemia; Alzheimer's disease

Sažetak
Background and aim: Risk factor occurrence in different types of dementia may indicate as to which type it is evolving and to early identify subjects at risk of cognitive loss. The aim of this pilot study was to determine the possible associations of specific single or multiple vascular risk factors in patients with AD and VAD. Patients and methods: Thirty-eight patients were included in the study: 16 with AD (8 men and 8 women, mean age 72, 19+- 6, 86 years), and 22 with VAD (14 women and 8 men, mean age 70, 20 +- 15, 50 years). Besides routine risk factor assessment, ultrasound measurements on common carotid artery (CCA) was done using Aloka ProSound ALPHA 10, with 13 MHz linear probe. Results: The frequency of RF among AD patients showed hyperlipoproteinaemia to be the most common (6 out of 16 patients) followed by arterial hypertension (AH) in 5/16, multiple RFs were present in 4 patients with AD (2 RF in one, and 3 or more RF in 3). In VAD group, AH was the most common RF (19 out of 22), followed by hyperlipoproteinaemia (12/22) and atial fibrillation. Two RF were registered simultaneously in 10 patients and 3 patients had 3 or more RFs at the time of assessment. Conclusion: Our results on a small sample of patients indicate that the frequency of vascular RFs tends to be more prominent in VAD, with multiple RFs (2 or more) present in more than half of the patients. Though vascular RFs contribute to both types of dementia, it is possible that the influence of particular multiple RF patterns could strongly contribute to pure vascular cognitive decline.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA