Pregled bibliografske jedinice broj: 373422
Determination of polyethylene glycols of different molecular weight in the stratum corneum
Determination of polyethylene glycols of different molecular weight in the stratum corneum // Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 811 (2004), 2; 177-182 (međunarodna recenzija, članak, znanstveni)
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Naslov
Determination of polyethylene glycols of different molecular weight in the stratum corneum
Autori
Jakaša, Ivone ; Calkoen, Florentine ; Kežić, Sanja
Izvornik
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (1570-0232) 811
(2004), 2;
177-182
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Polyethylene glycol (PEG); Tape stripping; Percutaneous penetration; Stratum corneum
Sažetak
We developed a sensitive method for determination of polyethylene glycols (PEGs) of different molecular weight (MW) in the human stratum corneum (SC) obtained by tape stripping. The analysis is based on derivatization with pentafluoropropionic anhydride (PFPA) and gas chromatography– electron capture detection (GC– ECD). The identification and quantification of PEGs was done using individual oligomers. The method showed to be suitable for studying permeability in normal and impaired skin with respect to MW in the range of 150– 600 Da.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE