Naslov
Magnesium andD Calcium in Exhaled Breath Condensate in Childern with Asthma and Gastroesophageal Reflux Disease

Autori
Vlašić, Željka ; Dodig, Slavica ; Čepelak, Ivana ; Zrinski Topić, Renata ; Živčić, Jadranka ; Nogalo, Boro ; Turkalj, Mirjana ; Plavec, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 2nd Congress of European Academy of Pediatrics - EAP ; u: Archives of Disease in Childhood 93 (2008) (S3) / - , 2008, 580-580

Skup
Congress of European Academy of Pediatrics - EAP (2 ; 2008)

Mjesto i datum
Nica, Francuska, 24.10.2008. - 28.10.2008

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
magnesium; calcium; exhaled breath condensate; child; asthma; GERD

Sažetak
Both cations, magnesium and calcium, respectively, play multiple dynamic role in lung function. The aim of the present study was to compare values of magnesium and calcium in exhaled breath condensate (EBC) of children with asthma and gastroesophageal reflux disease (GERD). EBC was collected from a total of 53 children, aged 7-14 years (17 healthy children, 22 asthmatic children, and 14 children with GERD). EBC was collected using an EcoScreen condenser (Erich Jaeger GmbH, Hoechberg, Germany). Concentration of magnesium and calcium was determined by standardized methods on an Olympus AU400 selective autoanalyzer using reagents from the same manufacturer. Asthmatic children have lower values of magnesium (30 μ mol/L) than healthy children (0.051 μ mol/L) and children with GERD (80 μ mol/L). The lowest value of calcium was found in healthy children (46 μ mol/L), in comparison with asthmatics (60 μ mol/L) and children with GERD (130 μ mol/L). Magnesium to calcium ratio was lower in asthmatic children (50) and in children with GERD (0.62) than in healthy children (1.11). These findings indicate that EBC could be used for noninvasively measurement of magnesium and calcium. Future studies should investigate clinical efficiency of magnesium and calcium determination in EBC.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija

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