Pregled bibliografske jedinice broj: 365857
Catalytic Promiscuity of Halohydrin Dehalogenase and its Application in Enantioselective Epoxide Ring Opening
Catalytic Promiscuity of Halohydrin Dehalogenase and its Application in Enantioselective Epoxide Ring Opening // ChemBioChem, 9 (2008), 7; 1048-1051 doi:10.1002/cbic.200700734 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 365857 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Catalytic Promiscuity of Halohydrin Dehalogenase and its Application in Enantioselective Epoxide Ring Opening
Autori
Hasnaoui-Dijoux, Ghannia ; Majerić Elenkov, Maja ; Lutje Spelberg, Jeffrey H. ; Hauer, Bernhard ; Janssen, B. Dick
Izvornik
ChemBioChem (1439-4227) 9
(2008), 7;
1048-1051
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Biocatalysis; Enantioselectivity; Epoxides; Halohydrin dehalogenase; Nucleophiles
Sažetak
Halohydrin dehalogenase is a highly promiscuous enzyme that can catalyze enantioselective epoxide ring opening with at least nine different anionic nucleophiles. Its capacity to form carbon-nitrogen, carbon-oxygen, carbon-sulfur, and carbon-carbon bonds makes it possible to use this enzyme for the preparation of a range of highly enantioenriched beta-substituted alcohols or derivatives thereof, including cyanoalcohols, nitroalcohols, and oxazolidinones.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982933-2908 - Kiralni građevni blokovi za biološki aktivne molekule. Sinteza i reaktivnost (Hameršak, Zdenko, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Maja Majerić Elenkov
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- AGRICOLA
