Naslov
Helicobacter pylori and Borrelia Burgdorferi Infections in Forestry Workers

Autori
Presečki, Vladimir ; Katičić, Miroslava ; Bolanča, Smilja ; Babuš, Vladimir ; Marušić, Marinko ; Prskalo, Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Gut. 39 (1996), suppl. 2 / S.n. - , 1996, A58-A58

Mjesto i datum
,

Vrsta sudjelovanja
Ostalo

Vrsta recenzije
Nije recenziran

Ključne riječi
Helicobacter pylori; Borrelia Burgdorferi; CF; ELISA; forestry workers

Sažetak
Aim of this study was to evaluate the seroprevalence of H.pylori and B.burgdorferi in different professions of forestry workers. A group of 266 healty forestry workers was studied. Subjects with history of previous ulcer or digestive disease were excluded. All positive for B.burgdorferi were tested for antibodies to T.pallidum to exclude syphilis. Specific antibodies to H.pylori were investigated with complement fixation (CF) and ELISA methods (CF positive:titers >1:30, ELISA index IgG >40%) and to B.burgdorferi with indirect immunofluorescent antibody (IFA) assay, enzyme immunoassay (EIA) and Dot Blot G test (IFA positive titers >1:64, EIA corrected absorbance >0,16, Dot Blot G test positive with Borrelia extract, HMV, flagellin p41, p39, Osp C). The measurement of IgG specific antibodies against H.pylori and B.burgdorferi yielded the following distribution: Profession N (%) H.pylori+ (%) B.burgdorferi+ (%) Forestry engineer 30 11,2 16 53,3 6 20,0 Forestry technician 58 21,8 30 51,7 16 27,5 Woodcutter 125 46,9 80 64,0 34 27,2 Driver 32 12,0 20 62,5 10 31,2 Worker 21 7,8 17 80,9 8 38,0 TOTAL 266 163 61,2 74 27,8 Two forestry workers had IFA weak positive B.burgdorferi IgG titer 1:64, EIA corrected absorbance <0,12 (non reactive) and Dot Blot G test positive only B.burgdorferi flagellin (p41) and significant seropositiveness to H.pylori (CF titer >1:60; ELISA index IgG >90%). Conclusions: Among professionals with a lower socioeconomic status (drivers, forestry workers) prevalence of H.pylori infection was higher. Cross-reactions H.pylori+ve sera and B.burgdorferi flagellin (p41) are possible; cross-reactions of fixed B.burgdorferi cells and flagellin have limited the reliability of B.burgdorferi serology tests.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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