Naslov
Four million newborn deaths: Is the global research agenda evidence-based?

Autori
Lawn, Joy E. ; Rudan, Igor ; Rubens, Craig

Izvornik
Early Human Development (0378-3782) 84 (2008), 12; 809-814

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neonatal; newborn; research; priority-setting; neonatal infections

Sažetak
Four million neonates die each year. These deaths are mostly in low-income countries, but neonatal mortality and morbidity are also a priority burden in high-income countries. Epidemiological evidence suggests newborn research would prioritise the poorest families ; birth and the first days of life ; major causes particularly infections, preterm birth and asphyxia ; and include preventive strategies as well as improved care. However research investment is not commensurate to burden, and there is a mismatch with current research priorities. South Asia and sub Saharan Africa, with 75% of the burden, expend around US$20 million per year on newborn research, a fraction of what is spent on a smaller proportion of health problem in rich countries. We propose a research pipeline of description, discovery, development of solutions and delivery of research with scale-up to reach the poorest families. Listing research options and applying quantitative scoring enables systematic, transparent research prioritisation. As well as a research pipeline, a “ people pipeline” is required to generate research capacity in low-income countries.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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