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Pregled bibliografske jedinice broj: 364438

A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing

Green, Richard E.; Malaspinas, Anna-Sapfo; Krause, Johannes; Briggs, Adrian W.; Johnson, Philip L. F.; Uhler, Caroline; Meyer, Matthias; Good, Jeffrey M.; Maričić, Tomislav; Stenzel, Udo et al.
A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing // Cell, 134 (2008), 3; 416-426 doi:10.1016/j.cell.2008.06.021 (međunarodna recenzija, članak, znanstveni)

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Naslov
A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing

Autori
Green, Richard E. ; Malaspinas, Anna-Sapfo ; Krause, Johannes ; Briggs, Adrian W. ; Johnson, Philip L. F. ; Uhler, Caroline ; Meyer, Matthias ; Good, Jeffrey M. ; Maričić, Tomislav ; Stenzel, Udo ; Prüfer, Kay ; Siebauer, Michael ; Burbano, Hernán A. ; Ronan, Michael ; Rothberg, Jonathan M. ; Egholm, Michael ; Rudan, Pavao ; Brajković, Dejana ; Kućan, Željko ; Gušić, Ivan ; Wikström, Må ; rten ; Laakkonen, Liisa ; Kelso, Janet ; Slatkin, Montgomery ; Svante, Pääbo

Izvornik
Cell (0092-8674) 134 (2008), 3; 416-426

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
ChemBio; DNA; Eco_Evol

Sažetak
A complete mitochondrial (mt) genome sequence was reconstructed from a 38, 000 year-old Neandertal individual with 8341 mtDNA sequences identified among 4.8 Gb of DNA generated from 0.3 g of bone. Analysis of the assembled sequence unequivocally establishes that the Neandertal mtDNA falls outside the variation of extant human mtDNAs, and allows an estimate of the divergence date between the two mtDNA lineages of 660, 000 ± ; 140, 000 years. Of the 13 proteins encoded in the mtDNA, subunit 2 of cytochrome c oxidase of the mitochondrial electron transport chain has experienced the largest number of amino acid substitutions in human ancestors since the separation from Neandertals. There is evidence that purifying selection in the Neandertal mtDNA was reduced compared with other primate lineages, suggesting that the effective population size of Neandertals was small.

Izvorni jezik
Engleski

Znanstvena područja
Etnologija i antropologija



POVEZANOST RADA

Projekti:
101-2690680-2270 - Korelacija paleolitika mezolitika i neolitika kontinentalne i primorske Hrvatske (Brajković, Dejana, MZOS ) ( CroRIS)
196-1962766-2751 - Populacijska struktura Hrvatske - antropogenetički pristup (Rudan, Pavao, MZOS ) ( CroRIS)

Ustanove:
Institut za antropologiju

Profili:

Avatar Url Dejana Brajković (autor)

Avatar Url Ivan Gušić (autor)

Avatar Url Željko Kućan (autor)

Avatar Url Pavao Rudan (autor)

Poveznice na cjeloviti tekst rada:

doi download.cell.com

Citiraj ovu publikaciju:

Green, Richard E.; Malaspinas, Anna-Sapfo; Krause, Johannes; Briggs, Adrian W.; Johnson, Philip L. F.; Uhler, Caroline; Meyer, Matthias; Good, Jeffrey M.; Maričić, Tomislav; Stenzel, Udo et al.
A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing // Cell, 134 (2008), 3; 416-426 doi:10.1016/j.cell.2008.06.021 (međunarodna recenzija, članak, znanstveni)
Green, R., Malaspinas, A., Krause, J., Briggs, A., Johnson, P., Uhler, C., Meyer, M., Good, J., Maričić, T. & Stenzel, U. (2008) A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing. Cell, 134 (3), 416-426 doi:10.1016/j.cell.2008.06.021.
@article{article, author = {Green, Richard E. and Malaspinas, Anna-Sapfo and Krause, Johannes and Briggs, Adrian W. and Johnson, Philip L. F. and Uhler, Caroline and Meyer, Matthias and Good, Jeffrey M. and Mari\v{c}i\'{c}, Tomislav and Stenzel, Udo and Pr\"{u}fer, Kay and Siebauer, Michael and Burbano, Hern\'{a}n A. and Ronan, Michael and Rothberg, Jonathan M. and Egholm, Michael and Rudan, Pavao and Brajkovi\'{c}, Dejana and Ku\'{c}an, \v{Z}eljko and Gu\v{s}i\'{c}, Ivan and Wikstr\"{o}m, M and \#229 and Laakkonen, Liisa and Kelso, Janet and Slatkin, Montgomery and Svante, P\"{a}\"{a}bo}, year = {2008}, pages = {416-426}, DOI = {10.1016/j.cell.2008.06.021}, keywords = {ChemBio, DNA, Eco\_Evol}, journal = {Cell}, doi = {10.1016/j.cell.2008.06.021}, volume = {134}, number = {3}, issn = {0092-8674}, title = {A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing}, keyword = {ChemBio, DNA, Eco\_Evol} }
@article{article, author = {Green, Richard E. and Malaspinas, Anna-Sapfo and Krause, Johannes and Briggs, Adrian W. and Johnson, Philip L. F. and Uhler, Caroline and Meyer, Matthias and Good, Jeffrey M. and Mari\v{c}i\'{c}, Tomislav and Stenzel, Udo and Pr\"{u}fer, Kay and Siebauer, Michael and Burbano, Hern\'{a}n A. and Ronan, Michael and Rothberg, Jonathan M. and Egholm, Michael and Rudan, Pavao and Brajkovi\'{c}, Dejana and Ku\'{c}an, \v{Z}eljko and Gu\v{s}i\'{c}, Ivan and Wikstr\"{o}m, M and \#229 and Laakkonen, Liisa and Kelso, Janet and Slatkin, Montgomery and Svante, P\"{a}\"{a}bo}, year = {2008}, pages = {416-426}, DOI = {10.1016/j.cell.2008.06.021}, keywords = {ChemBio, DNA, Eco\_Evol}, journal = {Cell}, doi = {10.1016/j.cell.2008.06.021}, volume = {134}, number = {3}, issn = {0092-8674}, title = {A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing}, keyword = {ChemBio, DNA, Eco\_Evol} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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