Naslov
Reproductive hormones in men with respect to blood lead and cadmium levels

Autori
Telišman, Spomenka ; Cvitković, Petar ; Ročić, Boris ; Prpić-Majić, Danica ; Pizent, Alica

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Heavy Metals in the Environment / Farmer, JG - Edinburgh : CEP Consultants, 1991, 13-16

ISBN
0 905941 47 0

Skup
The 8th International Conference on Heavy Metals in the Environment

Mjesto i datum
Edinburgh, Ujedinjeno Kraljevstvo, 09.1991

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Reproductive hormones in men; blood lead; blood cadmium

Sažetak
Follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, and estradiol were measured in the serum of 152 male volunteers: 51 subjects with no occupational exposure to lead or cadmium, and 101 subjects with slight to excessive occupational exposure to lead. Lead exposure assessment included: blood lead (PbB), activity of erythrocyte delta-aminolevulinic acid dehydratase (ALAD), and erythrocyte protoporphyrin (EP). Possible confounding factors: age, smoking habits, alcohol consumption, serum zinc (ZnS), serum copper (CuS), and blood cadmium (CdB) were evaluated. The results showed slight increases in testosterone and estradiol with respect to an increase in lead exposure (PbB, ALAD, EP), which remained significant after controlling for age, ZnS, CuS, CdB (which highly correlated with smoking habit), and alcohol consumption. Cigarette smoking/cadmium and alcohol consumption were found to somewhat influence the level of hormones. However, no impairment of male reproductive endocrine function was observed. With regard to the observed lead-induced decrease in sperm count in the same subjects, the results are in favour of our hypothesis of an increase in sperm destruction, rather than a decrease in sperm production, with respect to the increase in lead exposure in men.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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