Naslov
DIABETES MELLITUS AND CHRONIC LYMPHOCYTIC LEUKEMIA

Autori
Smircic-Duvnjak, Lea ; Metelko, Zeljko

Izvornik
Diabetologia Croatica (0351-0042) 28 (1999), 2; 81-83

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, ostalo

Ključne riječi
diabetes mellitus; chronic lymphocytic leukemia; comorbidity

Sažetak
Chronic lymphocytic leukemia (CLL) is a form of leukemia that most frequently occurs in Western countries. Its prevalence in diabetic patients is unknown. In an 81-year-old male diabetic patient who presented with severe inguinoscrotal ulceration, the presence of CLL made the diagnosis of diabetes and its complications questionable and aggravated the course of infection. The development of diabetes in the patient could be attributed to corticosteroid therapy, however, the hyperglycemic effect of chemotherapy could not be excluded either. Chemotherapy could also cause renal function impairment and polyneuropathy. The synergistic suppressive effect of diabetes and CLL on the infection fighting white cells contributed to the higher risk of infection and aggravated its course. The high prevalence of diabetes and CLL comorbidity, further studies are needed to assess the effect of chemotherapy on the level of glucose and development of diabetic complications.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA