Naslov
DIABETES MELLITUS AND ATHEROSCLEROSIS

Autori
Metelko Zeljko ; Pavlic-Renar Ivana ; Babic Zdravko

Izvornik
Diabetologia Croatica (0351-0042) 29 (2000), 1; 9-18

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
atherosclerosis; diabetes mellitus

Sažetak
Diabetes mellitus can be simply defined as an absolute or relative insulin deficiency (insulinopenia) with consequential hyperglycemia. Atherosclerosis is the most common arterial lesion characterized by local intimal thickenings that consist of multiplied and modified smooth muscle cells, macrophages, lipids from intra- and pericellular serum lipoprotein deposits, and multiplied connective tissue (collagen, elastin, mucopolysaccharides). Atherosclerotic cardiovascular disease is one of the most common complications of diabetes. Dislipoproteinemia, obesity, the lack of exercise, hypertension, cigarette smoking, psychological profile, and pattern of behavior are common risk factors for diabetes mellitus and atherosclerosis. Diabetes mellitus is a marked risk factor in the onset of atherosclerosis in its early stages, whereas atherosclerosis is a significant additional factor of exacerbation of late diabetes complications, with a mutual tendency of potentiating alterations. The recognition of various factors influencing the disease alterations and their dynamic monitoring are the only mode of satisfactory treatment.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA