Naslov
High prevalence of skin sensitization to inhalant allergens in school children from Zagreb, Croatia,
(Visoka prevalencija kožne senzitizacije na inhalacijske alergene u školske djece iz Zagreba, Hrvatska)

Autori
Stipić-Marković, Asja ; Pevec, B ; Pevec, MR ; Turkalj, Mirjana ; Zimić, Lukrica ; Čvorišćec, Branimir

Izvornik
Periodicum biologorum (0031-5362) 109 (2007), 2; 161-164

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Allergy ; senzitization ; prevalence ; inhallant allergen
(Alergija ; senzitizacija ; prevalencija ; inhalacijski alergen)

Sažetak
Background: The prevalence of allergic symptoms is lower among children living in the continental part of Croatia compared to those from the coastal region. We aimed to determine the prevalence of skin reactivity to inhalant allergens among children from continental Croatia. Subjects and Methods: Skin prick tests (SPTs) with 10 common inhalant allergens (Dcrmatophagoides pteronyssinus, Dermatophagoides farinae, cat, dog, mixed grasses, mixed trees, Ambrosia trifida, Alternaria tenuis, Cladosporium herbarum, and cockroach) were peiformed in 13-year-old children (7th grade) from 18 elementary schools in Zagreb. Results: A total of 384 children participated in the study. Positive SPT was recorded in 201 children (52.34%). Of those, 15.36%- were sensitized to one, 9.90%- to two, and 27.08%: to three or more allergens. D. pteronyssinus was the dominant allergen, causing sensitization in 56.22%> of atopic subjects. Prevalence of sensitization to other allergens was as follows: 40.307c mixed grasses, 39.80%c D. farinae, 36.317c Dog, 15.827c Cat, 32.837c A. trifida, 29.357c mixed trees, 17.41%c cockroach, 16.917c A. tenuis, and 12.437c C. herbarum. The most frequent sensitizers among monosensitized subjects were D. pteronyssinus and cockroach, causing sensitization in 27.127c and 16.95% of subjects, respectively. Conclusion: The percentage of positive skin reactivity to inhalant allergens teas much higher than the prevalence of allergic symptoms in Zagreb school population. House dust mite was the most dominant allergen. Prevalence of sensitization to cockroach was high. This result may serve as a reference to a practising allergologist and suggest the inclusion of cockroach allergens into the Croatian standard SPT panel.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Farmacija

POVEZANOST RADA