Naslov
Neurodevelopmental outcome and neuroimaging of children with congenital cytomegalovirus infection

Autori
Mejaški-Bošnjak, Vlatka ; Krakar, Goran ; Lončarević, Damir ; Đuranović, Vlasta ; Tešović, Goran ; Lujić, Lucija ; Marn, Borut

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 20th Annual Meeting of the EACD ; u: Developmental Medicine and Child Neurology 50 (2008) S114 ; 3-13 / - , 2008, 9-10

Skup
20th Annual Meeting of the EACD (20 ; 2008)

Mjesto i datum
Zagreb, Hrvatska, 05.06.2008. - 07.06.2008

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
neurodevelopment; CMV serology; PCR; cranial ultrasonography; brain MRI; cerebral malformation

Sažetak
The aim of this study is to present neurodevelopmental outcome and neuroimaging of 39 children with congenital cytomegalovirus (CMV) infection. Among them, 15 were symptomatic at neonatal age, while remaining 24 asymptomatic infants were referred afterwards (mean 3mo) for deviant neurological signs and/or gastrointestinal problems. CMV infection was confirmed by specific serology, PCR and/or urinary viral isolation. Here we present cranial US findings, i.e CMV „ markers“ in symptomatic and asymptomatic children. Cranial MRI performed additionally showed focal or widespread brain anomalies. All children had prospective neurodevelopmental follow-up undergoing repeated audiologic investigations, ophthalmologic, neurologic and developmental assessment. Infants who have asymptomatic congenital CMV infection at birth still have considerable risk of developing neurologic abnormalities. In both symptomatic and asymptomatic infants there is a wide spectrum of brain abnormalities consequent to neurodevelopmental outcome.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

Napomena
DOI: 10.1111/j.1469-8749.2008.00002.x-i1 ;

POVEZANOST RADA