Naslov
Brain MRI Abnormalities in Ataxia-Telangiectasia

Autori
Habek, Mario ; Brinar, Vesna ; Radoš, Marko ; Zadro, Ivana ; Žarković, Kamelija

Izvornik
Neurologist (1074-7931) 14 (2008); 192-195

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
ataxia-telangiectasia ; magnetic resonance imaging ; demyelination ; age

Sažetak
Introduction: Ataxia-telangiectasia (AT) is a rare autosomal recessive disorder, initially characterized by normal brain MRI. Case report: In a 34-year-old female patient with AT, magnetic resonance imaging (MRI) revealed extensive and diffuse white matter dismyelination, T1 and T2 hypointense lesions, T1 hypointense but T2 hyperintense lesions, and numerous dilated telangiectases upon gadolinium enhancement. Discussion: In our patient, brain MRI confirmed extensive extracerebellar lesions in AT. Conclusion: Our report broadens the spectrum of brain MRI abnormalities in AT and supports the hypothesis on cerebrovascular abnormalities occurring in later stages of AT.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA