Pregled bibliografske jedinice broj: 34688
Determination of Psychophysiological and Hormonal Disturbances in the Groups of Depressive and Nondepressive Alcoholics
Determination of Psychophysiological and Hormonal Disturbances in the Groups of Depressive and Nondepressive Alcoholics // The Fourth International Congress on Physiological Anthropology
Zagreb: Institute for Anthropological Research, 1998. str. 28-29 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 34688 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Determination of Psychophysiological and Hormonal Disturbances in the Groups of Depressive and Nondepressive Alcoholics
Autori
Ivica, Josip ; Stančić, Vladimir ; Rešetić, Josip ; Vrkljan, Milan ; Prstačić, Miroslav
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
The Fourth International Congress on Physiological Anthropology
/ - Zagreb : Institute for Anthropological Research, 1998, 28-29
Skup
The Fourth International Congress on Physiological Anthropology
Mjesto i datum
Zagreb, Hrvatska, 06.09.1998. - 10.09.1998
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Alcoholism; depression; psychophysiology; hormons
Sažetak
Acute and chronic alcohol intake and alcohol withdrawal induce disfunction of neuroendocrine and other regulatory system.. The aims of this study were to assess a possible HPA dysfunction in our population of alcoholics, using dexamethasone suppression test (DST). The serum and urinary cortisol were compared between the groups of 89 male patients (64.5 % depresive and 32 % nondepresive alcoholics) ( Hamilton test), before and after DST. In nondepressive patients, 50 % was nonsupressive in DST. In depressive patients 54 % was supressive in DST test( serum cortisol) . 24 hours urinary excretion in group of nondepresive patients was supressed only in 22 % of cases ; depressive patients showed 49.1 % nonsupresors. Basal serum cortisol secretion was significantly lower in group of nondepressive than depressive patients.Also, serum concentration at 16 h were significantly higher in group of the depressive nonsupressive patients. Basal urinary cortisol excretion was in normal range in all patients, but after dividing the patients in groups of supressors and nonsupressors, significantly higher (p<0,002) basal urinary cortisol concentrations were found in nonsupressive group.We concluded on the basis of DST test, as well basal cortisol measurement, the that the neuroendocrine disfunction of alcoholic patients could be present even the depression is still not pronounced.
Izvorni jezik
Engleski
