Naslov
Pathological changes in kidney biopsies from patients with plasma-cell dyscrasia

Autori
Bulimbašić, Stela ; Racar-Pačić, Arijana ; Galešić, Krešimir ; Sabljar-Matovinović, Mirjana ; Kovačević-Vojtušek, Ivana ; Horvatić, Ivica ; Ljubanović, Danica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Virchows Archiv / - , 2007

Skup
21. European Congress of Pathology

Mjesto i datum
Istanbul, Turska, 2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Plama cell dyscrasias; kidney disease

Sažetak
The plasma cell dyscrasia is frequently used as generic term for description of three distinct clinical entities: multiple myeloma, monoclonal gammopathy of unknown significance and dysproteinemia. They all have frequent renal involvement in common which can either present the first manifestation, or can occur later, during the course of disease. Morphological patterns of involvement vary, depending on which renal compartment is predominantly targeted. Commoner tubulopathic manifestation include Fanconi syndrome and cast nephropathy, while glomerular damage can be manifested as AL amyloidosis or monoclonal immunoglobin deposition disease. Using combination of light microscopy, immunoflourescence and electronic microscopy, all of them can be properly diagnosed in kidney biopsy, which is important for later clinical managment and therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA