Naslov
Inheritance of Hypodontia in Twins

Autori
Lapter, Marina ; Šlaj, Mladen ; Škrinjarić Ilija, Muretić, Želimir

Izvornik
Collegium Antropologicum (0350-6134) 22 (1998), 1; 291-297

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
hypodontia; twins; tooth development; congenital-anomalies; expression patterns; homeobox gene; msx1; induction; agenesis; palate; size

Sažetak
The aim of this study was to establish prevalence of hypodontia in the twin sample and to asses sthe degree of its heritability. a study was performed in a sample of 96 twin pairs, 38 pairs being monozygotic (MZ) and 58 pairs dizygotic (DZ), from north-west Croatia. The sample included 25.82% of all twins born in the region during ten-year period. the twin zygostiy was determined according to the WHO redommendations. A revised Holzinger index according to allen was applied to calculate the degree of heritability. Hypodontia was found in 22 out of the total of 192 twins analyzed (11.5%). Among 96 pairs of twins, hypodontia was observed in 17 pairs (7 MZ and 10 DZ pairs). among the MZ, 4 pairs were found to be concordant for hypodontia, among the DZ one pair only. the heritability index was 0825. a prevalence of hypodontia in twins observed in this study is significantly higher than in the general population. A high index of heritability (Hc =0.825) points to a high genetic determination.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

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