Naslov
Evaluation of aging vs. dementia by means of neurosonology

Autori
Demarin, Vida

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), stručni

Izvornik
Fifth International Congress on Vascular Dementia Final program and abstracts / - Ženeva : Karger Publishers, 2007, 54-55

Skup
Fifth International Congress on Vascular Dementia

Mjesto i datum
Budimpešta, Mađarska, 08.11.2007. - 11.11.2007

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Dementia; IMT; transcranial doppler; TCD

Sažetak
Vascular dementia (VD) includes a heterogeneous group of disorders in which vascular disease plays a vital role in the development of cognitive impairment. The term „ vascular aging“ was recently introduced, while the ideal strategy would be to confront the vascular disease before damage to the cerebral vasculature occurs. As neurosonology enables non-invasive assessment of the cerebrovascular system, it represents a valuable tool for distinction of vascular disease versus normal vascular aging. Subclinical artherosclerosis involves intima-media thickening (IMT), plaque formation and alterations in arterial mechanics and studies dealing with it are based on B mode ultrasound imaging. IMT measurement in the common carotid artery (CCA) may be used as a surrogate arterosclerotic marker. Increased IMT was shown to have positive correlation with mild decrement in cognitive scores in symptoms free individuals with vascular risk factors. Several observational studies have determined IMT as a possible predictor for future cerebrovascular events: Cardiovascular Health Study (CHS), Rotterdam Study and Atherosclerosis Risk in Communities Study (ARIC). As it appears that mechanical arterial properties, rather than hemodynamics, are affected first with aging, neurosonological methods can be used in the assessment of arterial mechanics of carotid arteries (carotid strain) enabling the screening of „ unsuccessful vascular aging“ and potentially reversible subclinical carotid atherosclerosis. Intracranial haemodynamic of the aging brain can sucessfully be assessed using Transcranial Doppler Sonography (TCD), functional TCD with various stress tests and TCD detection of cerebral emboli. Both intracranial and extracranial neurosonological methods are convenient, relatively inexpensive and widely available. This lecture will emphasize their increasing possibilities in detection, follow up and also in screening for early signs of cerebovascular disease. Neurosonology techniques provide informations necessary to closer determine the relation between cognitive deterioration and vascular risk factors, so that the evolution towards dementia could be prevented or at least postponed.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA