Naslov
Subtenonijalna primjena triamcinolona kod neovaskularnog oblika senilne makularne degeneracije
(Subtenonial application of triamcinolone in neovascular form of senile macular degeneration)

Autori
Lončarek, Karmen ; Brajac, Ines ; Štalekar, Hrvoje

Izvornik
Acta Medica Croatica (1330-0164) 61 (2007); 391-393

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Senilna makularna degeneracija; Koroidna neovaskularizacija; Subtenonijalna primjena; Triamcinolon
(Age-related macular degeneration; Choroid neovascularization; Sub-tenon application; Triamcinolone)

Sažetak
The aim of this prospective study was to investigate the effectiveness of sub-tenon application of triamcinolone for neovascular age-related macular degeneration. The study included 38 eyes (26 patients ; 14 women and 12 men, aged 63 to 82 years) with newly diagnosed subfoveal neovascular age-related macular degeneration. Each eye received sub-tenon injection of 0.5 mL suspension of triamcinolone-acetonide (20 mg of active substance). Follow up period was 12 months. After initial application, the injections were repeated on individual case, none to five times. Elevated intraocular pressure occurred in five patients (seven eyes) and was treated with topical antiglaucomatous therapy. Transient ptosis of upper eyelid occurred in one case and completely recovered in two days. The mean visual acuity was 0.13 +/- 0.17 on the beginning of the study and 0.22 +/- 0.22 at the end of the study. Visual acuity improved in 15/38 (39%) eyes, remained unchanged in 10/38 (26%) eyes, and worsened in 13/38 (35%) eyes. Improvement by three or more lines on Snellen optotype occurred in two cases. Comparing our results to those from other authors, sub-tenon application of triamcinolone did not prove as effective as when applied intravitreally, but is substantially less expensive and easier to perform.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

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