Pregled bibliografske jedinice broj: 336453
Correlation of Neurological Symptoms and Breath Holding Index Values in Patients With Severe Internal Carotid Stenosis
Correlation of Neurological Symptoms and Breath Holding Index Values in Patients With Severe Internal Carotid Stenosis // Acta clinica Croatica, 45 (2006), 4; 315-318 (međunarodna recenzija, članak, znanstveni)
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Naslov
Correlation of Neurological Symptoms and Breath Holding Index Values in Patients With Severe Internal Carotid Stenosis
Autori
Zavoreo, Iris ; Aleksić-Shibabi, Anka ; Demarin, Vida
Izvornik
Acta clinica Croatica (0353-9466) 45
(2006), 4;
315-318
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Moždane arterije - fiziopatologija; Bolesti karotidnih arterija - dijagnostika; Karotidna stenoza - ultrazvuk; Ultrazvuk; Dopplerov; transkranijski
(Cerebral arteries - physiopathology; Carotid artery diseases - diagnosis; Carotid stenosis - ultrasonography; Ultrasonography; Doppler; transcranial)
Sažetak
The aim of the study was to evaluate the role of cerebral vasoreactivity measurement in the follow up of patients with severe internal carotid stenosis. We used breath holding index (BHI) as a quantitative parameter of cerebral vasoreactivity and functional state of cerebral hemodynamics. We evaluated data of 150 patients with high grade carotid stenosis (definition according to standardized criteria of the Cerebrovascular Laboratory, Reference Center for Neurovascular Disorders of the Ministry of Health of Republic of Croatia). All patients underwent CDFI, TCD and CT/MR imaging tests, complete laboratory work-up, ECG, chest x-ray, and spinal tap in selected cases. CDFI and TCD findings were obtained in a standardized manner. BHI was calculated as percentage increase in mean blood flow velocity (MBFV) occurring during breath holding divided by the time (seconds) for which the subject hold his/her breath. All patients had verified recent ischemia of brain parenchyma on CT/MR scan. There were 29 (19%) symptom-free patients, 14 (9%) men and 15 (10%) women, who had BHI >0.7 ; 35 (24%) patients, 15 (10%) men and 20 (14%) women, with transient neurological symptoms, without recent ischemic lesions on CT/MR scan and BHI ≥ 0.7 ; and 86 (57%) patients with first ever stroke, 54 (36%) men and 32 (21%) women, who had hemispheric symptoms according to the site of stenosis (BHI <0.7). BHI is an easy and reproducible, real time method in the follow up of patients with severe carotid disease. It is very useful in predicting decompensation of intracranial collateral circulation, hemodynamic insufficiency and cerebrovascular accident.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
134-1340036-0033 - Uloga genetskih markera u razvoju cerebralne aterosklerotske bolesti (Demarin, Vida, MZOS ) ( CroRIS)
134-1340036-0034 - Funkcijska dijagnostika moždane cirkulacije (Lovrenčić-Huzjan, Arijana, MZOS ) ( CroRIS)
Ustanove:
KBC "Sestre Milosrdnice"
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
Uključenost u ostale bibliografske baze podataka::
- MEDLINE
