Naslov
Characteristics of electroencephalogram (EEG) in posttraumatic stress disorder (PTSD) in combat veterans treated with fluoxetine

Autori
Begić, Dražen ; Jakovljević, Miro ; Mihaljević-Peleš, Alma

Izvornik
Psychiatria Danubina (0353-5053) 13 (2001); 21-26

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
PTSD; qEEG; beta rhythm; fluoxetine

Sažetak
Rationale: There is an increasing number of evidence about the biological cause of posttraumatic stress disorder (PTSD). Quantitative electroencephalographic (qEEG) studies are the scarcest among such investigations. The aim of this investigation is to find out whether there are differences in qEEG characteristics between PTSD combat veterans and healthy subjects. Subjects and methods: Seventeen veterans with PTSD comprised the experimental group and twenty veterans without PTSD (and other psychiatric disturbances) were included in the control group. They were investigated by qEEG recordings. 10-s free artefact EEG interval was analyzed by FFT (fast Fourier transformation). Power values of particulary frequency band (delta, theta, alpha 1, alpha 2, beta 1, beta 2, beta 3) were observed on the regions: Fp1, Fp2, F3, F4, F7, F8, C3, C4, T3, T4, T5, T6, P3, P4, O1 and O2. PTSD patients treated only with fluoxetine in last 2 months. All subjects were medication free for a period of a least 2 weeks. Results: PTSD subjects had increased beta 1 activity over prefrontal, frontal and central regions ; and increased beta 2 activity over frontal, central and temporal sites. Conclusions: These results suggest about neurobiological basis of PTSD. Various explanations have been offered for beta activity increase observed in PTSD subjects. Results of this investigation point to the role of beta frequencies as the potential marker in PTSD.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA