Pregled bibliografske jedinice broj: 335204
Mesenhymal tumor in the sublingual area: fibrosarcoma or monophasic synovial sarcoma
Mesenhymal tumor in the sublingual area: fibrosarcoma or monophasic synovial sarcoma // Cytopathology / Kocjan, Gabrijela (ur.).
Oxford: Wiley-Blackwell, 2005. (poster, nije recenziran, sažetak, stručni)
CROSBI ID: 335204 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Mesenhymal tumor in the sublingual area: fibrosarcoma or monophasic synovial sarcoma
Autori
Kanic, Romina ; Kardum-Skelin, Ika ; Barto, V ; Manojlović, Spomenka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
Cytopathology
/ Kocjan, Gabrijela - Oxford : Wiley-Blackwell, 2005
Skup
31st European Congress of Cytology
Mjesto i datum
Pariz, Francuska, 02.10.2005. - 05.10.2005
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
Soft tissue sarcomas; FNAC; immunocytochemistry
Sažetak
Synovial sarcoma represents around 3% of all soft tissue sarcomas. but only 3-10% of them are found in head and neck area. They appear mostly as biphasic, whereas monophasic type is rare and represents greater differentially diagnostic problem because of its similarity, both in histological and in cytological presentation, to some other well differentiated mesenchymal tumors, firstly fibrosarcoma. It has characteristic chromosomal translocation t(X ; 18). Adult fibrosarcoma is also a rare tumor, it represents around 3% of all sarcomas, it doesn't have specific genelic abnormality, and is characterized by multiple chromosomal disturbances. Female patient O.M. 67 years old, called in because of the pain in the throat and temporomandibular area. Ultrasound and computerized tomography revealed expansive formation spreading in the right sublingual and submandibular region, with penetration into vallecula epiglollidis and recessus piriformis, 5 cm in diameter. FNA with immunocytochemistry (reaction positive to vimentin and negative to desmin, SMA, NSE, CD31, CD34, CD117, EMA) set the diagnosis of well differentiated mesenchymal tumor: well differenciated fibrosarcoma or MFH. After surgical excision patohistological finding was following: sarcoma- diff.dg.: monophasic synovial sarcoma or well differentiated fibrosarcoma. Our conclusion is that, since the final answer in subclassification of malignant soft tissue tumors cannot always be given by histopathology and immunohistochemistry, further cytogenetic and molecular analyses necessary.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
