Pregled bibliografske jedinice broj: 329121
Isothiocyanato boron dipyrromethenes - The first BODIPY analogues of fluorescein isothiocyanate
Isothiocyanato boron dipyrromethenes - The first BODIPY analogues of fluorescein isothiocyanate // Photochemistry and Photobiology, 82 (2006), 3; 746-749 doi:10.1562/2005-01-10-RA-769 (međunarodna recenzija, članak, znanstveni)
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Naslov
Isothiocyanato boron dipyrromethenes - The first BODIPY analogues of fluorescein isothiocyanate
Autori
Malatesti, Nela ; Hudson, Robert ; Smith, Karen ; Savoie, Huguette ; Rix, Katie ; Welham, Kevin ; Boyle, Ross W.
Izvornik
Photochemistry and Photobiology (0031-8655) 82
(2006), 3;
746-749
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Light; Fluorophores; Porphyrin; Probes; Dyes
Sažetak
Two boron complexes of 5-phenyldipyrromethenes bearing isothiocyanate groups on the phenyl ring have been synthesized for the first time. The utility of these new fluorescence probes for labeling biologically relevant proteins is demonstrated on two monoclonal antibodies that bind to antigens overexpressed on cancer cells. Spectral comparison of the two structures reveals significant photophysical differences, including bathochromically shifted excitation and emission bands, increased molar absorptivity and a large increase in fluorescence quantum yield of approximately 10 times. Differences in photophysical parameters are linked to hindered rotation of the phenyl ring in one of the probes.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
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- BIOSIS Previews (Biological Abstracts)
- CA Search (Chemical Abstracts)
- Genetics Abstracts
- GeoRef
- MEDLINE
- Nucleic Acids Abstracts
