Pregled bibliografske jedinice broj: 324431
QSPR and QSAR study of phthalimidohydroxamic acids
QSPR and QSAR study of phthalimidohydroxamic acids // Acta Pharmaceutica, 45 (1995), 15-24 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 324431 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
QSPR and QSAR study of phthalimidohydroxamic acids
Autori
Nikolić, Sonja ; Medić-Šarić, Marica ; Matijević-Sosa, Julija
Izvornik
Acta Pharmaceutica (1330-0075) 45
(1995);
15-24
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Lepidium sativum L. ; mitodepressive effect ; phthalimidohydroxamic acids ; QSAR ; QSPR
Sažetak
Newly prepared phthalimidohydroxamic acids are tested for their mitodepressive effect on the growth of Lepidium sativum L. seeds (Cresson). Their partition coefficients, log P(o/w), are calculated by Rekker method. In the structure-property-activity study we have used topological indices to predict the physico-chemical properties and bioactivity of the prepared compounds. The optimal QSPR and QSAR models are obtained by using the valence connectivity index and the information-theoretic index.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
